Dogbiotics™ DE-01 is the daily postbiotic powder that dissolves the sticky shield protecting bad-breath bacteria. Made with human-grade bone broth, organic pumpkin, and beef liver. Sprinkle 10 seconds. Dogs lick the bowl.
First postbiotic clinically studied in dogs for dental health
Reduces 9× more bad bacteria than placebo (3 published studies)
Sprinkle 10 seconds a day. No brushing. No fighting.
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Step 1. Pick Your Dog's Weight
* Multiple dogs? Go up one weight class per dog.
Step 2. Choose Your Supply
1 Month Supply
Starter|$1.67 / day
$99.00$49.97
Most Popular
3 Months Supply
Best Value|$1.11 / day
+ Free Shipping
$299.00$99.96Save $199
5 Months Supply
Bulk Save|$1.00 / day
+ Free Shipping
$499.00$149.97Save $349
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Step 1. Pick Your Dog's Weight
* Multiple dogs? Go up one weight class per dog.
Step 2. Choose Your Supply
1 Month Supply
Starter|$1.33 / day
$99.00$39.98
Most Popular
3 Months Supply
Best Value|$0.89 / day
+ Free Shipping
$299.00$79.97Save $219
5 Months Supply
Bulk Save|$0.80 / day
+ Free Shipping
$499.00$119.98Save $379
DeliversSat, 16 May· Free shipping
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Tiny dogs under 6 lbs
½ scoop
Small dogs 6 to 25 lbs
1 scoop
Medium dogs 26 to 75 lbs
2 scoops
Large dogs 76+ lbs
3 scoops
Instructions. Serve as a topper on your dog's meal, or mix in, once per day. Introduce gradually with half the recommended serving for the first 3 to 5 days.
Store in a cool, dry place. Always provide fresh water. Consult your vet if needed. Not for dogs with thyroid issues.
DE-01 Postbiotic Strain
Modulates oral microbiome bacteria. The first postbiotic clinically studied in dogs for dental health.
Hero Ingredient
Why Dogs Actually Eat It
Beef Bone Broth PowderPalatability + minerals
Beef Liver PowderReal food, real flavor
Functional Support
Organic PumpkinGut-friendly fiber
Organic KelpMineral support
Oat Flour (GF)Gentle carrier
ChlorellaGreens + detox support
Organic Parsley LeafBreath support
Zinc CitrateOral health mineral
Patent-Pending
No Artificial Colors
No Artificial Flavors
No Fillers
FDA-Registered Facility
Vet-Formulated
★ ★ ★
Why 30,000+ Dogs Choose Dogbiotics Every Month?
...They Skip the Vet Bill. They Skip the Anesthesia. And every scoop is:
Fresher Breath
She can lean in for a kiss.
Stronger Gums
Healthy pink, not angry red.
Less Plaque
Brown buildup, reversed.
Clinically Studied
3 published studies in dogs.
Vet-Formulated
Built with veterinary insight.
Human-Grade
The same standard you eat.
★ ★ ★
Formulated by Vets. Loved by Pets.
Emma's gums were getting worse. The vet wanted $2,000 to put her under for a cleaning. That terrified me. So we tried this powder instead. Sprinkled it on her food. Two weeks later her breath was fresher and the brown buildup was gone. A simple thing that actually works.
Becca R.
Durham, North Carolina
Verified
★ ★ ★
Science backed ingredients. Without the junk.
Hero Ingredient
Canine Oral Health Postbiotic (COHP)
A breakthrough postbiotic clinically shown to reduce plaque, bad breath, and support a healthy oral microbiome. Where true dental health begins.
Fights plaque and tartar by disrupting biofilms
Neutralizes bad breath at the microbial level
Balances the oral microbiome for lasting gum health
Trace Minerals
Organic Kelp (Ascophyllum nodosum)
Ocean-sourced trace minerals that traditionally support gum health and oral defense.
Palatability
Organic Pumpkin
Naturally sweet fiber that helps dogs love the powder on their food. Easy on the stomach.
Palatability
Grass-Fed Beef Bone Broth
Grass-fed bone broth for flavor and collagen. Dogs lick the bowl. Owners stop fighting.
Breath
Organic Parsley Powder
Chlorophyll-rich greens that freshen breath from the inside, not just on the surface.
Detox Support
Chlorella
Pure green algae for natural detox support and oral microbiome balance.
Gum Defense
Zinc Citrate
A mineral that helps maintain healthy gums and supports your dog's natural oral defense.
★ ★ ★
Dogbiotics Leads the Future of Pet Health
Our formula is built on cutting-edge science, vet insight, and a relentless commitment to quality. Every ingredient is chosen for what it does. Cleaner teeth. Healthier gums. Fresher breath. Better long-term health for your dog. No fillers. No gimmicks. Just real results, backed by research.
Clinically Validated
Three peer-reviewed published studies. Supports a healthy oral microbiome.
Vet Formulated
Built with leading veterinarians for long-term dental health.
Lab Tested
Tested for quality and safety on every batch.
30,000+ Dog Parents
Trusted by 30,000+ dog parents who skip the vet bill.
Most dental products fight your dog's mouth from the outside. Chews scrape the surface. Brushing reaches what your dog will tolerate. Water additives mask the smell. None of them reach where the bacteria actually live. DE-01 works from inside the oral microbiome.
Reaches What Chews Can'tBacteria coat themselves in a sticky biofilm. Chews and brushes hit the shield, not the bacteria. DE-01 disrupts that shield from below. In lab studies, it broke down 98% of oral biofilm, outperforming zinc and spirulina by more than 2X.
Rebalances the Oral Microbiome, SelectivelyIn published clinical research, DE-01 reduced 9 times more odor-causing bacteria than placebo, targeting only the bad-breath species and leaving the healthy oral microbiome intact.
Works From the Inside, All DayThe postbiotic absorbs into your dog's saliva at mealtime and keeps working while your dog eats, sleeps, and plays. The mouth gets cleaner from the inside out, without brushing and without fighting.
A Simple 10-Second Daily RoutineSprinkle one scoop over your dog's regular food. Dogs love the bone broth and liver flavor, and most lick the bowl clean. Match the dose to your dog's size.
Results You Can Count On
Clinical studies on our powerful postbiotic proved a significant improvement in bad breath and plaque accumulation.
Cleaner teeth
Fresher breath
Healthier smiles
10-second daily routine
01Month 1
Starting your new dental routine. Many dog parents report fresher breath within weeks.
02Month 2
Stronger gums, and a generally healthier, happier dog.
03Month 3
A cleaner, fresher, whiter smile. Let the good times roll!
Dogbiotics Rises Above the Rest
dogbiotics
Leading Alternatives
9 Premium Active Ingredients
Delicious Taste from Whole Foods
100% Human Grade Ingredients
Clinically Validated Postbiotic
60 Scoops in Every Jar
Zero Fillers, Chemicals, Additives
Certified Organic Ingredients
Frequently asked questions
Everything you want to know before you commit.
How It Works
How does this help my dog's breath?
DE-01 contains a clinically studied postbiotic that rebalances your dog's oral microbiome — the real source of bad breath. Instead of masking odors, it targets the bacteria causing them at the gum line. Most dog parents notice a meaningful difference within the first 7 days.
Will this help my dog's existing plaque?
Yes. The postbiotic in DE-01 disrupts the biofilms that plaque and tartar build on. It won't dissolve heavy calculus overnight, but consistent daily use typically shows visible improvement in plaque accumulation and gum health around weeks 4–6.
How is this different than dental chews or sticks?
Dental chews work by mechanical abrasion — the chewing physically scrapes the tooth surface, but only on the outer face. They don't reach below the gum line, between teeth, or into the oral microbiome. DE-01's postbiotic works biologically, targeting the bacteria that cause plaque, tartar, and bad breath at the source — while your dog eats their regular meal.
Will it prevent future dental issues?
That's exactly what it's designed for. By keeping the oral microbiome balanced daily, you're stopping the bacterial buildup that leads to plaque, tartar, and gum disease before it starts. Think of it like brushing — the benefit compounds over time. Dogs who use it consistently tend to get much cleaner vet checks.
Using DE-01
How often should I use DE-01™ Dental Dogbiotic?
Once daily, sprinkled over your dog's regular food. That's it — 10 seconds, same time every day.
How long until I can expect to see whiter teeth?
Most dog parents notice fresher breath within the first week. Visible improvement in plaque and whitening typically shows up around weeks 4–6 of daily use. The 90-day mark is where the full transformation is most dramatic — cleaner teeth, healthier gums, and a noticeably fresher mouth at the vet.
Will my dog like the taste?
Almost universally, yes. The formula is made with grass-fed beef bone broth and liver, so most dogs eat it right up. Even picky eaters tend to have no issues with this one.
How long should I use it for?
Daily, ongoing — just like brushing. The benefit comes from consistency. Once your dog's oral health improves, daily use keeps it there and prevents the bacterial buildup from returning.
How many servings are in 1 jar?
60 scoops per jar. For most medium-sized dogs (25–75 lbs), that's a 30-day supply at the recommended daily dose.
Can I mix it with wet food, homemade food, or bone broth?
Absolutely. Sprinkle the scoop over whatever your dog is eating — kibble, wet food, raw, homemade, or stirred into bone broth. The key is that your dog consumes it with their meal.
Safety & Ingredients
What are the ingredients?
The active ingredient is our clinically studied postbiotic dental strain. The formula also contains grass-fed beef bone broth and liver for palatability. All ingredients are human-grade — no artificial additives, no fillers, no synthetic preservatives. The full ingredient list is printed on every jar.
Does it contain sodium hexametaphosphate or other chemicals?
No. Sodium hexametaphosphate is a synthetic chelating agent found in many commercial dental foods and treats. We don't use it. DE-01 contains no synthetic chemicals, no artificial preservatives, and no fillers — human-grade ingredients only.
Is this safe for puppies?
Yes, though we recommend waiting until your puppy has finished teething — typically around 6–7 months. After that, the daily routine is appropriate for dogs of any age.
Is DE-01™ Dental Dogbiotic safe for cats?
DE-01 is formulated specifically for dogs. We don't recommend it for cats — the dosing and formulation are dog-specific, and some ingredients may not be suitable for felines.
Where is this made? Where is it shipped from?
Made in the USA. We ship from our US fulfillment center — most orders arrive within 3–5 business days.